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Hard Tissue Preparation
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Hard Tissue Preparation

Experimental implant research is the implantation of small implants in the bones of animals. The purpose is to examine how a given treatment effects the fixation of an implant. The fixation of an implant can, among others, be illustrated by the use of ”biomechanical push-out test” and ”histomorphometry”. In order to execute these tests, the bones containing the implants have to go through a time-consuming preparation:

The implant bone block is divided in two by means of the Exact bone saw. Half of the block is immediately frozen to -20°C and saved for later use in the "biomechanical push-out test”. The other half is dehydrated in alcohol, colored with basic fusin, and embedded in plastic (polymethylmetacrylate). When embedded, 20-30 µm thin slices are cut off the implant bone block. These slices are used for ”histomorphometric” analysis.

The preparation and cutting of bone containing implants is a technically demanding procedure performed by experienced laboratory technicians at the Orthopaedic Research Lab.

 
Band Saw

Exact Apparatebau
2000 Nordenstadt
Germany

 
Kalender

Publikationer
Oxford consensus on primary cam morphology and femoroacetabular impingement syndrome: part 1-definitions, terminology, taxonomy and imaging outcomes
Dijkstra HP, Mc Auliffe S, Ardern CL, Kemp JL, Mosler AB, Price A, Blazey P, Richards D, Farooq A, Serner A, McNally E, Mascarenhas V, Willy RW, Oke JL, Khan KM, Glyn-Jones S, Clarke M, Greenhalgh T, Agricola R, Andersen TE, Ayeni O, Beasley I, Bizzini M, Cardinale M, Chiokwindo T, de Villiers R, Engebretsen L, Entwisle T, Ergen E, Fernquest S, Geertsema C, Gimpel M, Haddad F, Hanff D, Heerey J, Holmich P, Impellizzeri FM, Jacobsen JS, van Rensburg CJ, Kassarjian CJ, Khanduja V, Kliethermes S, Lewis C, Maak T, Mayes S, Mechlenburg I, Mkumbuzi N, Nelis S, Palmer A, Papadopoulou T, Philippon M, Pierpoint L, Plass L, Pollock N, Reiman M, Roberts N, Rommers N, Sawaya N, Snoxell T, Souza J, Strickland L, Taseska T, Thorborg T, Thornton J, Tol J, Trease L, van Klij P, Volcke P, Weir A, Wilson F, Yamauchi Y
Risk stratification for post-operative pulmonary complications following major cardiothoracic or abdominal surgery: Validation of the PPC Risk Prediction Score for physiotherapist's clinical decision-making.
Salling SL, Jensen JH, Mosegaard SB, Sørensen L, Mechlenburg I.
Whole exome sequencing of 28 families of Danish descent reveals novel candidate genes and pathways in developmental dysplasia of the hip.
Dembic M, van Brakel Andersen L, Larsen MJ, Mechlenburg I, Søballe K, Hertz JM.
 Ortopædkirurgisk Forskning Aarhus Universitetshospital Palle Juul-Jensens Boulevard 99 Indgang J 8200 Aarhus N Tel: +45 7846 7471 
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